As with many new scientific findings that upset the established apple cart of accepted principles, the early reactions to the announcement in 1970 of a discovery of “a fourth major state of consciousness” (in articles in Science, American Journal of Physiology, and Scientific American),1were mixed. Those who had actually experienced the transcendent state were delighted to read science was recognizing its validity. Previous anecdotal reports of this experience had been dismissed by skeptics, who insisted, quite rightly, that if these reported subjective experiences of “transcendence” were to be credible, more than just “anecdotal,” they’d have to have objectively measurable physical counterparts.As it turned out, they do.